Dulcolax and the other Bisacodyl suppositories have the same active ingredient (10mg Bisacodyl) as The Magic Bullet. The base, or carrier of the active ingredient in the suppository is what makes the different. The Magic Bullet uses a Polyethylene Glycol base which is water-soluble. This base allows the Bisacodyl to be activated by the body’s own moisture shortly after insertion. The Dulcolax and other Bisacodyl suppositories use a vegetable oil base. This type of base takes longer to work because it needs time to be melted by the body's heat.